منابع مشابه
Genetic Causes of Generalized Epilepsies.
Generalized epilepsies, particularly the idiopathic or genetic generalized epilepsies (GGEs), represent some of the most common epilepsies. Clinical genetic data including family studies and twin studies provide compelling evidence for a prominent genetic impact. The first decade of the 21st century was marked by progress in understanding the basic biology of generalized epilepsies including ge...
متن کاملEpidemiology of idiopathic generalized epilepsies.
Idiopathic generalized epilepsies (IGEs) are a relatively new category of disorders defined by strict clinical and electroencephalogram (EEG) features proposed by the International League Against Epilepsy (ILAE) classification of epileptic syndromes. IGEs are usually easy to diagnose when clinical and EEG data are collected, but epilepsy is not synonymous with epileptic syndrome. So far, IGEs a...
متن کاملEEG-fMRI of idiopathic and secondarily generalized epilepsies.
We used simultaneous EEG and functional MRI (EEG-fMRI) to study generalized spike wave activity (GSW) in idiopathic and secondary generalized epilepsy (SGE). Recent studies have demonstrated thalamic and cortical fMRI signal changes in association with GSW in idiopathic generalized epilepsy (IGE). We report on a large cohort of patients that included both IGE and SGE, and give a functional inte...
متن کاملThe profusion of genotypes and phenotypes in "idiopathic" generalized epilepsies.
The myriad genetic associations with idiopathic (primary) generalized epilepsies (IGE) are challenging to both researchers and caregivers. There are numerous mutations, among them voltagegated sodium, potassium, and calcium channels and ligand-gated GABA receptors. A variety of mutations may produce similar phenotypes, while, equally troublesome, single mutations may produce a range of phenotyp...
متن کاملElectroencephalographic generalized features in idiopathic childhood focal epilepsies
PURPOSE Idiopathic focal epilepsies in childhood including benign childhood epilepsy with occipital paroxysms (BEOP) or benign childhood epilepsy with centro-temporal spikes (BCECTS) are characterized by specific focal electrographic patterns as the name indicates. Generalized spike-wave discharges in children with idiopathic focal epilepsy can suggest a neurobiological continuum with the idiop...
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ژورنال
عنوان ژورنال: Epilepsia
سال: 1998
ISSN: 0013-9580,1528-1167
DOI: 10.1111/j.1528-1157.1998.tb05115.x